40 years after serial killer Michael Myers attacked her and her friends, Laurie Strode (Jamie Lee Curtis) is now a paranoid shut-in, hellbent on revenge at the cost of her relationship with daughter Karen and granddaughter Allyson.

When Myers breaks free and escapes for one final night of terror, Laurie and her family — along with residents of Haddonfield and survivors of the original 1978 events — will need to band together to defeat him once and for all.